Table of Contents
1 Table of Contents
1 Table of Contents 5
1.1 List of Tables 6
1.2 List of Figures 6
2 Introduction 7
2.1 Introduction 7
2.1.1 High Levels of Product Diversification in a Highly Competitive Market Environment 7
2.1.2 Inconsistent Clinician Prescribing Preferences 7
2.1.3 Ongoing Market Shift Towards Abuse-Resistant Product Formulations 8
2.1.4 Increasingly Vocal Physician Associations Raise Concerns About Extent of Opioid Abuse 9
2.1.5 Full Commercial Potential of Transdermal Patches May Have Yet to be Fully Exploited 9
3 Overview of Currently Marketed Products 10
3.1 Major Marketed Products 10
3.1.1 Oxycontin 10
3.1.2 Exalgo 10
3.1.3 Onsolis 10
3.1.4 Duragesic 11
3.1.5 Opana ER 11
3.1.6 Vicodin CR 11
3.1.7 Dolophine Hydrochloride 11
3.1.8 Oxecta 11
3.1.9 Actiq 12
3.1.10 Embeda 12
3.1.11 Kadian 12
3.1.12 Avinza 12
3.2 Market Drivers and Barriers 13
3.2.1 Drivers 14
3.2.2 Barriers 15
4 Pipeline Analysis 17
4.1 Introduction 17
4.2 Opioid Compounds in the Developmental Pipeline 20
4.3 Distribution by Route of Administration 23
4.4 Promising Pipeline Products 26
4.4.1 ARX-01, AcelRX Pharmaceuticals 26
4.4.2 ALO-02, Pfizer 26
4.4.3 Zohydro ER, Zogenix 26
4.4.4 ELI-216, Elite Pharmaceuticals 27
4.4.5 BEMA Buprenorphine 27
4.4.6 CEP-33237, Cephalon 27
5 Deals Analysis 28
5.1 Overview: 28
5.1.1 M&As by Year 28
5.1.2 M&As by Value 29
5.1.3 Major M&As 30
5.2 Licensing Agreements 33
5.2.1 Licensing Agreements by Year 33
5.2.2 Licensing Agreements by Value 34
5.2.3 Major Licensing Agreements 35
5.3 Co-Development Agreements 38
5.3.1 Deals by Year 38
5.3.2 Major Co-Development Deals 39
6 Appendix 40
6.1 Abbreviations 40
6.2 Bibliography 41
6.3 Research Methodology 41
6.3.1 Coverage 41
6.3.2 Secondary Research 42
6.3.3 Primary Research 42
6.3.4 Pipeline Analysis 42
6.3.5 Expert Panel Validation 42
6.4 Contact Us 43
6.5 Disclaimer 43
List Of Figures
Figure 1: Opioids Market, Drivers and Barriers, 2012 13
Figure 2: Opioids Market, Global, R&D Pipeline by Phase (%), 2012 17
Figure 3: Opioids Market, Pipeline Analysis,,Opioid Compounds in Phase III 20
Figure 4: Opioids Market, Pipeline Analysis,,Opioid Compounds in Phase II 21
Figure 5: Opioids Market, Pipeline Analysis,,Opioid Compounds in Phase I 22
Figure 6: Opioids Market, Pipeline Analysis, Route of Administration for Pipeline Molecules Currently in Phase III 23
Figure 7: Opioids Market, Pipeline Analysis, Route of Administration for Pipeline Molecules Currently in Phase II 24
Figure 8: Opioids Market, Pipeline Analysis, Route of Administration for Pipeline Molecules Currently in Phase I 25
Figure 9: Opioids Market, M&As by Year, 2005–2012 28
Figure 10: Opioids Market, M&As by Value ($m), 2005–2012 29
Figure 11: Opioids Market, Licensing Agreements by Year, 2005–2012 33
Figure 12: Opioids Market, Licensing Agreements by Value ($m), 2005–2012 34
Figure 13: Opioids Market, Co-Development Agreements by Year, 2005–2012 38
List Of Tables
Table 1: Opioids Market, Global, R&D Pipeline Analysis by Phase, 2012 18
